Mental health condition

Addiction and Substance Use Disorders

Addiction, or substance use disorder, is a treatable medical condition affecting the brain and behavior. Learn the signs, risk factors and evidence-based treatment options.

What is addiction?

Addiction — clinically called substance use disorder — is a medical condition in which a person continues to use alcohol or drugs despite harmful consequences. It involves changes in brain systems related to reward, motivation, stress and self-control. It is treatable, and many people recover.

Signs

Signs of a substance use disorder can include:

  • Using more, or for longer, than intended
  • Wanting to cut down but being unable to
  • Spending a lot of time obtaining, using or recovering from a substance
  • Cravings
  • Continuing to use despite problems at work, school, home or with health
  • Needing more to get the same effect (tolerance), or withdrawal symptoms when stopping

These signs can occur with substance use disorders, but only a qualified professional can provide a diagnosis.

Causes and risk factors

Genetics, early exposure to substances, trauma, chronic stress and other mental health conditions are associated with a higher risk. Substance use disorders commonly occur alongside anxiety, depression and PTSD, and treating both together tends to work best.

Treatment

  • Behavioral therapies such as CBT, motivational interviewing and contingency management.
  • Medications for some substance use disorders, including opioid and alcohol use disorders.
  • Medically supervised withdrawal when needed.
  • Peer and family support, including mutual-help groups and family therapy.

Care can be outpatient, intensive outpatient, residential or inpatient depending on needs. See our guide to addiction treatment options.

Find care

Find care for addiction

Compare types of care — from online therapy to psychiatry — and learn what to consider before choosing a provider.

Explore care options

When to seek professional help

Consider contacting a doctor or licensed mental health professional if:

  • You want to cut down or stop but find you can’t.
  • Substance use is affecting your health, work, relationships or finances.
  • You experience withdrawal symptoms when you stop — stopping some substances, such as alcohol or benzodiazepines, suddenly can be dangerous, so seek medical advice.

Only a qualified professional can make a diagnosis, and reaching out early is always reasonable.

If you’re thinking about harming yourself or are in immediate danger, call your local emergency number. In the US, call or text 988 (Suicide & Crisis Lifeline).Crisis resources in other countries.

Explore care options

Frequently asked questions

Where can I find confidential help in the US?
The SAMHSA National Helpline (1-800-662-4357) is free, confidential and available 24/7 in English and Spanish for treatment referrals and information. You can also search FindTreatment.gov.
Are there medications that help with addiction?
Yes. For opioid use disorder and alcohol use disorder in particular, there are FDA-approved medications that can reduce cravings, support recovery and lower the risk of overdose. A healthcare professional can explain the options.

References

We rely on government health agencies, professional medical organizations, peer-reviewed research and academic institutions. Read our sourcing standards.

  1. Substance Use and Co-Occurring Mental Disorders(opens in a new tab)

    National Institute of Mental Health (NIMH)Government health agency

  2. Drug Misuse and Addiction(opens in a new tab)

    National Institute on Drug Abuse (NIDA)Government health agency

  3. National Helpline(opens in a new tab)

    Substance Abuse and Mental Health Services Administration (SAMHSA)Government health agency

About this article

Written by

ExploreMentalHealth Editorial Team

Our editors research and write every article using government health agencies, professional medical organizations and peer-reviewed research, following our published editorial standards.

First published
September 4, 2026
Last updated
September 19, 2026
Last medically reviewed
Review pending